Fumonisin B1 Toxicity in Grower-Finisher Pigs: A Comparative Analysis of Genetically Engineered Bt Corn and non-Bt Corn by Using Quantitative Dietary Exposure Assessment Modeling
2011

Fumonisin B1 Toxicity in Pigs: Comparing Bt Corn and Non-Bt Corn

publication Evidence: moderate

Author Information

Author(s): James E. Delgado, Jeffrey D. Wolt

Primary Institution: Iowa State University

Hypothesis

Does the source of corn (Bt vs non-Bt) affect the toxicity of fumonisin B1 in grower-finisher pigs?

Conclusion

Diets containing Bt corn present less potential to induce fumonisin B1 toxicity compared to diets with non-Bt corn.

Supporting Evidence

  • Pigs fed Bt corn showed better performance compared to those fed non-Bt corn.
  • The chronic toxicological level of concern for FB1 is 1.0 mg/kg of diet.
  • Diets with non-Bt corn posed the greatest risk for exceeding the toxicological level of concern.

Takeaway

This study found that pigs eating corn from genetically modified plants are less likely to get sick from a harmful toxin than those eating regular corn.

Methodology

The study used quantitative dietary exposure assessment modeling with both deterministic and semi-stochastic approaches to analyze FB1 toxicity in different corn diets.

Limitations

The study did not include environmental factors that could affect FB1 levels, and the DDGS concentration factor may be an overestimate.

Digital Object Identifier (DOI)

10.3390/ijerph8083179

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