Novel norovirus recombinants and of GII.4 sub-lineages associated with outbreaks between 2006 and 2010 in Belgium
2011

Norovirus Outbreaks in Belgium (2006-2010)

Sample size: 164 publication 10 minutes Evidence: moderate

Author Information

Author(s): Mathijs Elisabeth, Denayer Sarah, Palmeira Leonor, Botteldoorn Nadine, Scipioni Alexandra, Vanderplasschen Alain, Thiry Etienne, Dierick Katelijne

Primary Institution: University of Liege, Belgium

Hypothesis

What are the genetic variations and epidemiological patterns of norovirus outbreaks in Belgium from 2006 to 2010?

Conclusion

Noroviruses in Belgium showed significant genetic diversity and the emergence of new variants, which may contribute to increased outbreak frequency.

Supporting Evidence

  • Noroviruses were responsible for 11.8% of all suspected foodborne outbreaks in Belgium from 2006 to 2010.
  • GII.4 was the predominant genotype found in the outbreaks.
  • The number of reported norovirus outbreaks increased significantly in 2010.

Takeaway

Noroviruses are germs that can make people very sick with stomach problems, and this study found many different types of these germs in Belgium over four years.

Methodology

Stool samples from patients were analyzed for norovirus presence and genetic variation through RT-qPCR and phylogenetic analysis.

Limitations

The study primarily focused on human-to-human transmission and did not fully explore foodborne transmission.

Participant Demographics

Patients from foodborne outbreak investigations in Belgium.

Digital Object Identifier (DOI)

10.1186/1743-422X-8-310

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