Multimodal Therapy in Multidrug-Resistant Prostatitis: A Case Report and Review of the Literature
2024

Multimodal Therapy for Multidrug-Resistant Prostatitis

Sample size: 1 publication Evidence: low

Author Information

Author(s): Muacevic Alexander, Adler John R, Renaud Elise, Nagassar Rajeev P, Persaud Satyendra

Primary Institution: Sangre Grande Hospital, Sangre Grande, TTO; University of the West Indies, Saint Augustine, TTO

Hypothesis

Can intraprostatic injections combined with intravenous antibiotics effectively treat chronic bacterial prostatitis resistant to standard antibiotic therapy?

Conclusion

Intraprostatic injections combined with intravenous antibiotics successfully cleared the patient's multidrug-resistant recurrent prostatitis.

Supporting Evidence

  • Chronic bacterial prostatitis is difficult to treat and often recurs after antibiotic therapy.
  • The patient had multiple prior antibiotic treatments before the new approach was tried.
  • Intraprostatic injections were guided by ultrasound to ensure accurate delivery of the medication.
  • The treatment led to sterile urine and semen cultures eight weeks later.
  • The patient remained asymptomatic for two years following treatment.

Takeaway

A man with a tough prostate infection got better after doctors injected medicine directly into his prostate and gave him antibiotics through an IV.

Methodology

The patient received intraprostatic injections of a mixture of lidocaine, amikacin, and meropenem, along with intravenous meropenem for four weeks.

Limitations

The study is based on a single case report, limiting generalizability.

Participant Demographics

33-year-old male with a history of renal tract issues and recurrent urinary tract infections.

Digital Object Identifier (DOI)

10.7759/cureus.74025

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