Development and evaluation of formulations of microbial biotransformed extract of tobacco leaves for hair growth potential
2010

Hair Growth Potential of Tobacco Leaf Extracts

Sample size: 30 publication Evidence: moderate

Author Information

Author(s): Ashlesh V. Murkute, Mahesh S. Sahu, Prashant Y. Mali, Vinod D. Rangari

Primary Institution: J. L. Chaturvedi College of Pharmacy

Hypothesis

The study aims to evaluate the hair growth potential of microbial biotransformed extract of tobacco leaves in male albino wister rats.

Conclusion

The microbial biotransformed extract of tobacco leaves increases hair growth in a concentration-dependent manner.

Supporting Evidence

  • The formulations showed an increase in hair growth and serum total protein in a concentration-dependent manner.
  • Serum total testosterone decreased according to a concentration-dependent manner.
  • Microbial biotransformation of tobacco leaves in cow urine was effective for hair growth promotion.

Takeaway

This study found that using a special extract from tobacco leaves can help hair grow better in rats.

Methodology

The extract was prepared by microbial biotransformation of tobacco leaves in cow urine for 28 days, and various concentrations of herbal lotions were applied to shaved skin areas of rats for 30 days.

Limitations

Further investigations are necessary to explore structural elucidation, characterization, clinical safety, reliability, and molecular mechanisms.

Participant Demographics

Male albino wister rats were used in the study.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.4103/0974-8490.72328

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