Cancer risks among long-standing spouses
2002

Cancer Risks Among Long-Standing Spouses

Sample size: 71020 publication Evidence: moderate

Author Information

Author(s): Kari Hemminki, Ying Jiang

Primary Institution: Department of Biosciences at Novum, Karolinska Institute

Hypothesis

Do spouses who have lived together for a long time share similar cancer risks due to their shared environment?

Conclusion

The study found that spouses do not share significant cancer risks, except for a few associations related to known risk factors.

Supporting Evidence

  • Only three cancer sites showed increased risks among spouses: stomach, lung, and bladder.
  • Concordant cancer risks were modest, with standardized incidence ratios ranging from 1.19 to 1.38.
  • Shared lifestyle factors like smoking were linked to some cancer associations between spouses.

Takeaway

This study looked at couples who lived together for a long time and found that they don't really share cancer risks, except for a few types of cancer that are linked to things like smoking.

Methodology

The study used the Swedish Family-Cancer Database to analyze cancer risks among spouses who lived together for at least 15 years and had children together.

Potential Biases

Potential bias due to ecological study design and reliance on existing databases.

Limitations

The study lacked dietary data and could not account for differences in dietary habits over long periods of cohabitation.

Participant Demographics

Couples who had one or more children in common and lived together for at least 15 years.

Statistical Information

Confidence Interval

95% CI

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1038/sj.bjc.6600302

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