Celmanax™ Reduces E. coli O157:H7 in Cattle
Author Information
Author(s): Baines Danica, Erb Stephanie, Lowe Ross, Turkington Kelly, Sabau Emil, Kuldau Gretchen, Juba Jean, Masson Luke, Mazza Alberto, Roberts Ray
Primary Institution: Lethbridge Research Centre
Hypothesis
Can the prebiotic Celmanax™ reduce E. coli O157:H7 colonization in cattle and mitigate the effects of mycotoxins in feed?
Conclusion
The study found that Celmanax™ effectively decreased E. coli O157:H7 colonization and associated cytotoxicity in bovine cells.
Supporting Evidence
- Cattle developed Jejunal Hemorrhage Syndrome after consuming feed with mycotoxigenic fungi.
- Celmanax™ removed cytotoxicity in vitro associated with feed extracts.
- 0.1% Celmanax™ significantly reduced E. coli O157:H7 colonization in mucosal explants.
Takeaway
Cattle that ate moldy feed got sick, but a special supplement called Celmanax™ helped keep them healthier by fighting off bad germs.
Methodology
The study involved in vitro assays to test the effects of Celmanax™ and Dairyman's Choice™ on E. coli O157:H7 colonization and cytotoxicity in bovine cells.
Limitations
The study was conducted in vitro, and results may not fully translate to in vivo conditions.
Participant Demographics
Dairy cattle from multiple production sites in Southern Alberta, Canada.
Statistical Information
P-Value
0.001
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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