Fluoroquinolone-Resistant Group B Streptococci in Acute Exacerbation of Chronic Bronchitis
2008

Fluoroquinolone-Resistant Group B Streptococci in Chronic Bronchitis

Sample size: 1 publication Evidence: moderate

Author Information

Author(s): Tazi Asmaa, Gueudet Thomas, Varon Emanuelle, Gilly Liliane, Trieu-Cuot Patrick, Poyart Claire

Primary Institution: Assistance Publique-Hôpitaux de Paris

Hypothesis

Is there a fluoroquinolone-resistant strain of Group B Streptococci in patients with acute exacerbation of chronic bronchitis?

Conclusion

The study identifies a fluoroquinolone-resistant strain of Group B Streptococci in a patient with chronic bronchitis, highlighting a growing concern for antibiotic resistance.

Supporting Evidence

  • The strain was isolated from sputum samples of a patient treated with levofloxacin.
  • The strain showed high resistance to certain fluoroquinolones.
  • DNA analysis revealed a mutation associated with fluoroquinolone resistance.

Takeaway

A patient with chronic bronchitis had a type of bacteria that didn't respond to a common antibiotic, which is a worrying sign for treating infections.

Methodology

The study involved isolating and testing a strain of Group B Streptococci from sputum samples for antibiotic resistance.

Participant Demographics

An 80-year-old man with chronic bronchitis.

Digital Object Identifier (DOI)

10.3201/eid1402.071006

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