State and territory immunization program activities and their association with human papillomavirus vaccine initiation in the United States of America: A multilevel approach
2024

Impact of Immunization Programs on HPV Vaccine Uptake

Sample size: 17390 publication Evidence: moderate

Author Information

Author(s): Colón-López Vivian, Muñoz-Torres Francisco J., Escabí Wojna Erika, Vega Jimenez Idamaris, Díaz Miranda Olga L., Medina-Laabes Diana T., Wells Katelyn, Ortiz Ana P., Hull Pamela C., Suárez Erick

Primary Institution: University of Puerto Rico Comprehensive Cancer Center

Hypothesis

This study evaluates the association between immunization program activities aimed at increasing HPV vaccination among adolescents and their impact on initiation rates.

Conclusion

Immunization program activities significantly influence HPV vaccine initiation rates among adolescents in the USA.

Supporting Evidence

  • States that made school-based adolescent coverage rates available to the public had higher HPV vaccine initiation rates.
  • States that expanded the number of pharmacies entering HPV vaccination data showed increased initiation rates.
  • HPV initiation prevalence was significantly higher among younger adolescents in states with specific immunization activities.

Takeaway

The study found that certain activities by health programs can help more kids get their HPV vaccine, which is important for preventing cancer.

Methodology

The study used a multilevel Poisson model to analyze data from the 2016 AIM Annual Survey and the 2019 National Immunization Survey–Teen.

Potential Biases

Potential biases in the NIS-Teen survey and reliance on provider-reported vaccination data.

Limitations

The study lacked operational definitions for IP activities and relied on provider-reported HPV vaccination histories, which may lead to underestimations.

Participant Demographics

Participants included 52.4% males, 62.2% aged 13-15 years, and 76.2% had mothers with more than high school education.

Statistical Information

Confidence Interval

95% CI: 1.02, 1.14

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pgph.0002852

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication