Testing Verbal Response Scales for Chronic Rhinosinusitis Symptoms
Author Information
Author(s): Keeley Tom, Gaw Nina, Ahmed Waseem, Alfonso-Cristancho Rafael, Sousa Ana R., Forde Katie, Sharp Rosie, Whyman Sophie, Gater Adam
Primary Institution: GSK, London, UK
Hypothesis
This study assessed the content validity and meaningful change in verbal response scales used to assess chronic rhinosinusitis with nasal polyps symptom severity.
Conclusion
The CRSwNP symptom verbal response scales effectively assess relevant symptoms experienced by patients, supporting their content validity.
Supporting Evidence
- Participants reported nasal obstruction as the most bothersome symptom.
- 100% of participants understood the VRS items.
- Most participants considered a one-category improvement in symptoms as meaningful.
- The study included a diverse sample from multiple countries.
- Qualitative analysis revealed key symptoms relevant to patients' experiences.
Takeaway
This study found that using words to describe symptoms of a nose condition helps patients understand and report their feelings better.
Methodology
Qualitative, semi-structured interviews were conducted with adults diagnosed with moderate-to-severe CRSwNP to assess the content validity of verbal response scales.
Potential Biases
Potential educational imbalance among participants may affect the generalizability of findings.
Limitations
The study was retrospective and may introduce bias; further quantitative assessment of meaningful change is needed.
Participant Demographics
Participants were aged 18 and older, with a mix of genders and educational backgrounds, primarily from the US, Germany, and China.
Digital Object Identifier (DOI)
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