Trajectories in waist circumference and waist-to-height ratio with left ventricular hypertrophy in childhood
2024

Waist Size and Heart Health in Kids

Sample size: 946 publication 10 minutes Evidence: high

Author Information

Author(s): Jin Xuli, Zhao Min, Sun Jiahong, Xi Bo

Primary Institution: Shandong University

Hypothesis

The study aims to estimate the association of trajectories in waist circumference and waist-to-height ratio with left ventricular hypertrophy during childhood.

Conclusion

Rapid increases in waist circumference or waist-to-height ratio during childhood significantly increase the risk of left ventricular hypertrophy.

Supporting Evidence

  • Children in the high-increasing waist circumference group had a significantly higher left ventricular mass index.
  • Children with increasing waist-to-height ratio trajectories also showed a higher risk of left ventricular hypertrophy.
  • The study followed participants over multiple time points to assess changes in waist measurements and heart health.
  • Findings suggest that early intervention is crucial to prevent cardiovascular damage in children.

Takeaway

If kids' waist sizes grow too fast, it can hurt their hearts, even if they later slim down.

Methodology

The study used group-based trajectory modeling to categorize waist circumference and waist-to-height ratio into different trajectory groups and analyzed their associations with left ventricular mass index and left ventricular hypertrophy using regression analyses.

Potential Biases

Potential unmeasured confounders like family history of cardiovascular disease and air pollutants may have influenced the results.

Limitations

The study used convenience sampling from a specific school, which may limit generalizability, and relied on self-reported data for lifestyle behaviors, which could introduce bias.

Participant Demographics

51.9% of participants were boys, with an average age of 8 years at baseline.

Statistical Information

P-Value

p<0.05

Confidence Interval

95% CI: 4.37, 5.95

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3389/fnut.2024.1506191

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