Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman Disease): A case report and review of 49 cases with fine needle aspiration cytology
2011

Case Report on Rosai-Dorfman Disease

Sample size: 49 publication Evidence: moderate

Author Information

Author(s): Shi Yuquan MD, PhD, Griffin Adrienne Carruth MD, Zhang Paul JL MD, Palmer James N MD, Gupta Prabodh MBBS, MD, FIAC

Primary Institution: Hospital of the University of Pennsylvania

Conclusion

Rosai-Dorfman disease is a rare condition that can be diagnosed effectively using fine needle aspiration cytology.

Supporting Evidence

  • The patient had a diagnosis of inflammatory pseudotumor before being correctly diagnosed with RDD.
  • FNA revealed typical features of RDD, leading to the correct diagnosis.
  • The study reviewed 49 cases of RDD diagnosed by FNA, highlighting its diagnostic utility.

Takeaway

Rosai-Dorfman disease is a rare illness that can cause swollen lymph nodes and other symptoms, and doctors can often diagnose it with a simple needle test.

Methodology

The study involved a case report and a review of 49 cases diagnosed by fine needle aspiration cytology.

Limitations

FNA may lead to misdiagnosis due to limited sampling and lack of tissue architecture examination.

Participant Demographics

The case involved a 79-year-old female patient.

Digital Object Identifier (DOI)

10.4103/1742-6413.76731

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