Neurotrophins and Neurodegenerative Diseases
Author Information
Author(s): Muacevic Alexander, Adler John R, Mansoor Sadia, Jindal Anushka, Badu Nana Yaw Afriyie, Katiki Chiko, Ponnapalli V Jaswitha S, Desai Kesha J, Nassar Sondos T
Hypothesis
This study aims to explain the most current findings about the function of neurotrophins in neurodegenerative diseases and their therapeutic applications.
Conclusion
Neurotrophins could serve as promising targets for therapeutic intervention that may stop or even reverse the development of neuropathology associated with neurodegenerative illnesses.
Supporting Evidence
- Neurodegenerative diseases cause significant morbidity and disability globally.
- Neurotrophins play a crucial role in neuroplasticity and neurogenesis.
- Current studies show limited data on the efficacy of neurotrophins in clinical trials.
Takeaway
Neurotrophins are special proteins that help brain cells grow and stay healthy, and they might help treat diseases like Alzheimer's and Parkinson's.
Methodology
This systematic review followed PRISMA 2020 guidelines and included studies published in English within the last ten years, focusing on neurotrophins in neurodegenerative diseases.
Limitations
The review only included studies published in English and did not consider animal studies, which may have excluded relevant research.
Digital Object Identifier (DOI)
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