Adaptation and validation of the Portuguese version of the Lithium Knowledge Test (LKT) of bipolar patients treated with lithium: cross-over study
2006

Validation of the Portuguese Lithium Knowledge Test for Bipolar Patients

Sample size: 106 publication Evidence: moderate

Author Information

Author(s): Rosa Adriane R, Andreazza Ana Cristina, Gazalle Fernando Kratz, Sanchez-Moreno Jose, Santin Aida, Stein Airton, Barros Helena MT, Vieta Eduard, Kapczinski Flávio

Primary Institution: Centro de Pesquisas, Clinic Hospital of Porto Alegre, Brazil

Hypothesis

The Portuguese version of the Lithium Knowledge Test (LKT) will effectively assess lithium knowledge among bipolar patients.

Conclusion

The LKT is a reliable tool for evaluating lithium knowledge in bipolar patients, showing good internal consistency, sensitivity, and specificity.

Supporting Evidence

  • The LKT showed a mean score of 9.0 for men and 8.74 for women.
  • The sensitivity of the LKT was 84% and specificity was 81%.
  • There was a significant correlation between LKT scores and plasma lithium levels.

Takeaway

This study created a test to see how much bipolar patients know about lithium, which helps them take their medicine correctly.

Methodology

The study involved administering the LKT to 106 bipolar patients on lithium treatment and analyzing its internal consistency, validity, sensitivity, and specificity.

Potential Biases

Potential selection bias as non-adherent patients may not have participated.

Limitations

The study may not represent all bipolar patients, and it only assessed knowledge at one point in time.

Participant Demographics

73 women (68.9%) and 33 men (31.1%), mean age 43.56 for women and 41.61 for men.

Statistical Information

P-Value

0.020

Statistical Significance

p = 0.020

Digital Object Identifier (DOI)

10.1186/1745-0179-2-34

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