Endocrine correlates of male breast cancer risk: a case-control study in Athens, Greece
2000

Endocrine Factors and Male Breast Cancer Risk

Sample size: 99 publication Evidence: moderate

Author Information

Author(s): Petridou E, Giokas G, Kuper H, Mucci L A, Trichopoulos D

Primary Institution: Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA; Department of Hygiene and Epidemiology, University of Athens Medical School, Goudi, Athens, Greece

Hypothesis

Are certain endocrine-related variables associated with male breast cancer risk?

Conclusion

The study suggests that endocrine factors may play a significant role in the development of male breast cancer.

Supporting Evidence

  • There were significant inverse associations with smoking.
  • There were significant inverse associations with birth order.
  • There were significant inverse associations with reported frequency of orgasms in later life.

Takeaway

This study looked at men with breast cancer and healthy men to see if certain health factors were linked to cancer risk. It found that things like smoking and how often men reported having orgasms might be important.

Methodology

The study compared 23 cases of male breast cancer with 76 healthy male controls.

Participant Demographics

23 cases of male breast cancer and 76 healthy male controls.

Statistical Information

P-Value

P = 0.0004

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1054/bjoc.2000.1467

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication