Intensity modulated radiotherapy for elderly bladder cancer patients
2011

Radiotherapy for Elderly Bladder Cancer Patients

Sample size: 19 publication 10 minutes Evidence: moderate

Author Information

Author(s): Hsieh Chen-Hsi, Chung Shiu-Dong, Chan Pei-Hui, Lai Siu-Kai, Chang Hsiao-Chun, Hsiao Chi-Huang, Wu Le-Jung, Chong Ngot-Swan, Chen Yu-Jen, Wang Li-Ying, Hsieh Yen-Ping, Shueng Pei-Wei

Primary Institution: Far Eastern Memorial Hospital, Taipei, Taiwan

Hypothesis

To evaluate treatment planning using intensity-modulated radiotherapy (IMRT) and helical tomotherapy (HT) for elderly patients with bladder cancer.

Conclusion

IMRT and HT provide good locoregional progression-free survival with tolerable toxicity for elderly patients with invasive bladder cancer.

Supporting Evidence

  • Median survival was 21 months for the patients.
  • 89.5% of patients had no local recurrence.
  • 2-year overall survival rates were 26.3% for IMRT and 37.5% for HT.

Takeaway

Doctors used special radiation techniques to treat older people with bladder cancer, and they found that these methods worked well without causing too much harm.

Methodology

The study involved 19 elderly patients treated with either IMRT or HT, comparing their outcomes to conventional radiation therapy.

Limitations

The study had a small sample size and was retrospective in nature.

Participant Demographics

Median age was 80 years, with 14 men and 5 women.

Statistical Information

P-Value

0.004

Statistical Significance

p = 0.004

Digital Object Identifier (DOI)

10.1186/1748-717X-6-75

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