Management and Clinical Outcome of Penetrating Keratoplasty for Long-Term Corneal Changes in Sympathetic Ophthalmia
2011

Visual Outcomes of Penetrating Keratoplasty in Sympathetic Ophthalmia

Sample size: 3 publication Evidence: moderate

Author Information

Author(s): Ramamurthi Saraswathi, Obi Ebube E., Dutton Gordon N., Ramaesh Kanna

Primary Institution: Tennent Institute of Ophthalmology, Glasgow, UK

Hypothesis

Can penetrating keratoplasty restore vision in patients with sympathetic ophthalmia?

Conclusion

Penetrating keratoplasty can restore useful vision in stable sympathetic ophthalmitis cases, depending on the extent of the pathology.

Supporting Evidence

  • All three patients achieved a BCVA of 6/36 or better at one year follow-up.
  • The grafts remained clear with no recurrence of uveitis or rejection.
  • Immunosuppressive therapy was necessary to prevent graft rejection.

Takeaway

Doctors can help people with a specific eye problem called sympathetic ophthalmia see better by doing a special eye surgery.

Methodology

Interventional case series of three patients diagnosed with sympathetic ophthalmitis who underwent penetrating keratoplasty.

Potential Biases

Potential bias due to the small number of cases and the specific patient demographics.

Limitations

The study is limited by the small sample size and the high-risk factors for graft failure in the patients.

Participant Demographics

Three patients with a history of sympathetic ophthalmitis and previous eye surgeries.

Digital Object Identifier (DOI)

10.1155/2011/439025

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