High-Potency Prenatal Cannabis Exposure and Birth Outcome Measures
2024

Effects of Prenatal Cannabis Use on Newborns

Sample size: 72 publication 10 minutes Evidence: moderate

Author Information

Author(s): Kleinhans Natalia M., Johnson Allegra J., Larsen Sarah F., Berkelhamer Sara K., Larimer Mary E., Dager Stephen R.

Primary Institution: University of Washington

Hypothesis

Prenatal cannabis exposure (PCE) is associated with altered birth outcomes in obstetrically low-risk women.

Conclusion

Prenatal cannabis exposure is linked to lower birth weight and shorter length for gestational age in newborns.

Supporting Evidence

  • PCE newborns weighed less than controls, at the 38th percentile for weight.
  • PCE newborns were shorter for gestational age, at the 40th percentile for length.
  • Female PCE newborns had smaller head circumference compared to male PCE newborns.

Takeaway

Using cannabis during pregnancy can make babies smaller and shorter than expected.

Methodology

Observational cohort study comparing birth outcomes of newborns exposed to cannabis versus controls.

Potential Biases

Polysubstance use verification relied on self-reporting.

Limitations

Small sample size and inconsistent group matching.

Participant Demographics

Pregnant women aged 21-40 from Washington and Oregon.

Statistical Information

P-Value

0.04

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/children11121436

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication