Solid tumors of the pancreas can put on a mask through cystic change
2011

Cystic Changes in Solid Pancreatic Tumors

Sample size: 376 publication Evidence: moderate

Author Information

Author(s): Paik Kwang Yeol, Choi Seong Ho, Heo Jin Seok, Choi Dong Wook

Primary Institution: The Catholic University of Korea, Yeouido St. Mary's Hospital; Samsung Medical Center, Sungkyunkwan University School of Medicine

Hypothesis

Can solid pancreatic tumors manifest as cystic lesions?

Conclusion

Cystic changes in pancreatic solid tumors are rare but should be considered in diagnosis.

Supporting Evidence

  • Out of 376 patients, 10 tumors were identified as cystic lesions.
  • Six cases were pancreatic ductal adenocarcinoma (PDAC) with cystic degeneration.
  • Two cases were solid pseudopapillary tumors (SPT) that underwent complete cystic change.
  • One case was a cystic pancreatic endocrine tumor (PET) and one was a cystic schwannoma.

Takeaway

Sometimes, tumors in the pancreas can look like cysts instead of solid lumps, which can make them harder to identify.

Methodology

A retrospective review of medical records and pathologic findings of 376 patients who underwent pancreatic solid tumor resections from 2000 to 2006.

Limitations

The study only included cases from a single center and may not represent broader populations.

Participant Demographics

Mean age of patients with PDAC cystic changes was 62.7 years, with a mix of male and female patients.

Digital Object Identifier (DOI)

10.1186/1477-7819-9-79

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