The presentation and management of post-partum choriocarcinoma
1999

Managing Post-Partum Choriocarcinoma

Sample size: 9 publication Evidence: high

Author Information

Author(s): Dobson L S, Gillespie A M, Coleman R E, Hancock B W

Primary Institution: Trophoblastic Disease Screening and Treatment Centre, YCR Section of Clinical Oncology, Whitham Road, Sheffield, S10 2SJ, UK

Hypothesis

Can post-partum choriocarcinoma be effectively treated with chemotherapy?

Conclusion

All patients with post-partum choriocarcinoma were successfully treated with multiagent chemotherapy.

Supporting Evidence

  • Post-partum choriocarcinoma is a rare complication of pregnancy.
  • All patients presented with persistent primary or secondary post-partum haemorrhage.
  • Treatment with multiagent chemotherapy was successful in all cases.
  • Early diagnosis is important for effective treatment.

Takeaway

Post-partum choriocarcinoma is a rare condition that can be treated successfully with chemotherapy if diagnosed early.

Methodology

Analysis of nine consecutive patients treated at a specialized center.

Participant Demographics

Patients presented with post-partum choriocarcinoma after full-term non-molar pregnancies.

Digital Object Identifier (DOI)

10.1038/sj.bjc.6690244

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