Highly brominated anthracenes as precursors for the convenient synthesis of 2,9,10-trisubstituted anthracene derivatives
2008
Synthesis of Brominated Anthracene Derivatives
publication
Evidence: high
Author Information
Author(s): Cakmak Osman, Aydogan Leyla, Berkil Kiymet, Gulcin Ilhami, Buyukgungor Orhan
Primary Institution: Gaziosmanpasa University
Hypothesis
Can highly brominated anthracenes be used as precursors for synthesizing 2,9,10-trisubstituted anthracene derivatives?
Conclusion
The study successfully demonstrates an efficient synthesis of hexabromide 3 and tribromide 12, which can be used to create various anthracene derivatives.
Supporting Evidence
- The synthesis of hexabromide 3 was achieved in 95% yield without other stereoisomers.
- Tribromide 12 was produced in 75% yield through a base-induced elimination reaction.
- The methodology allows for the selective preparation of various anthracene derivatives.
Takeaway
The researchers found a new way to make special types of anthracene compounds using bromine without needing a catalyst.
Methodology
The study involved bromination of 9,10-dibromoanthracene and subsequent reactions to produce various anthracene derivatives.
Digital Object Identifier (DOI)
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