Comparing Heart Scans: MPS vs. LGE
Author Information
Author(s): Lene Rosendahl, Peter Blomstrand, Jan L Ohlsson, Per-Gunnar Björklund, Britt-Marie Ahlander, Sven-Åke Starck, Jan E Engvall
Primary Institution: Dept. of Clinical Physiology, County Hospital Ryhov, Sweden
Hypothesis
How do myocardial perfusion single photon emission computed tomography (MPS) and late gadolinium enhancement magnetic resonance imaging (LGE) compare in assessing myocardial infarct size?
Conclusion
MPS and LGE agree moderately in determining infarct size, with MPS showing slightly larger volumes.
Supporting Evidence
- MPS showed a slightly larger infarct volume than LGE.
- The correlation coefficients between methods for infarct size and extent were 0.71 and 0.63 respectively.
- WMSI determined with cine-MRI correlated moderately with infarct volume and extent.
Takeaway
Doctors used two different types of heart scans to see how much heart damage there was, and they found that one scan showed a bit more damage than the other.
Methodology
The study involved 40 patients who underwent both MPS and LGE to compare infarct volume and extent.
Potential Biases
Potential bias due to the selection of patients based on perfusion defects, which may not always indicate true myocardial scars.
Limitations
Some patients had a considerable time span between MPS and LGE exams, and patient selection was based on the presence of a perfusion defect, which could be due to attenuation artefacts.
Participant Demographics
33 men and 7 women, average age 65 ± 10 years.
Statistical Information
P-Value
0.01
Confidence Interval
95% CI for difference: -12.7 to -2.3
Statistical Significance
p = 0.01
Digital Object Identifier (DOI)
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