IMOP Study: Outpatient Cervical Ripening with Isosorbide Mononitrate
Author Information
Author(s): Bollapragada Shrikant, Mackenzie Fiona, Norrie John, Petrou Stavros, Reid Margaret, Greer Ian, Osman Inass, Norman Jane E
Primary Institution: Glasgow Royal Infirmary
Hypothesis
The use of outpatient IMN will result in a shorter inpatient stay before delivery, decreased costs to the health service, and greater maternal satisfaction with ripening and induction of labour, compared with placebo treatment.
Conclusion
The trial aims to determine if outpatient IMN can improve the induction of labour process, potentially leading to shorter hospital stays and higher satisfaction among women.
Supporting Evidence
- Outpatient cervical ripening with prostaglandins is associated with shorter admission to delivery times.
- Women report higher satisfaction rates with outpatient compared to inpatient cervical ripening.
- IMN has been shown to be effective in inducing cervical ripening without adverse fetal heart rate abnormalities.
Takeaway
This study is testing if a medicine called IMN can help pregnant women get ready for labor at home instead of in the hospital, which might make them happier and save money.
Methodology
Women scheduled for induction of labour will be randomised to self-administer either IMN 40 mg or a placebo at home before hospital admission.
Participant Demographics
Women scheduled for induction of labour at term, primarily nulliparous and with a Bishop Score ≤ 6.
Statistical Information
P-Value
p<0.008
Statistical Significance
p<0.008
Digital Object Identifier (DOI)
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