Construction, Deployment, and Usage of the Human Reference Atlas Knowledge Graph for Linked Open Data
2025

Human Reference Atlas Knowledge Graph for Linked Open Data

publication

Author Information

Author(s): Bueckle Andreas, Herr Bruce W., Hardi Josef, Quardokus Ellen M., Musen Mark A., Börner Katy

Primary Institution: Cold Spring Harbor Laboratory

Conclusion

The Human Reference Atlas Knowledge Graph serves as a comprehensive resource for biological data, covering numerous organs and structures.

Supporting Evidence

  • The HRA KG covers 71 organs and includes over 10 million nodes and 171 million edges.
  • It provides standard terminologies for describing biological structures and datasets.
  • The knowledge graph supports cross-scale biological queries using SPARQL.

Takeaway

Scientists created a big database that helps understand the human body better by organizing lots of information about organs and cells.

Methodology

The study involved developing a knowledge graph that integrates various biological data using standard terminologies and data structures.

Digital Object Identifier (DOI)

10.1101/2024.12.22.630006

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