Impact of Liver Disease on Weight Loss After Bariatric Surgery
Author Information
Author(s): Sabench Fatima, Rusu Elena Cristina, Clavero-Mestres Helena, Arredondo-Prats Vicente, Veciana-Molins Marina, Muñiz-Piera Sara, Vives Margarita, Aguilar Carmen, Bartra Elia, París-Sans Marta, Alibalic Ajla, Quintillà Maria Teresa
Primary Institution: Hospital Universitari Sant Joan de Reus, Reus, Spain
Hypothesis
Is weight loss after bariatric surgery influenced by the presence of MASLD/ MASH?
Conclusion
MASLD does not significantly affect short-term weight loss outcomes post-bariatric surgery, but long-term results show variability.
Supporting Evidence
- Patients without liver disease lose more weight than those with liver disease after sleeve gastrectomy.
- Weight regain after surgery can worsen liver disease or delay its improvement.
- Standardized reporting practices are essential for future research.
Takeaway
This study looked at how liver disease affects weight loss after weight loss surgery. It found that while liver disease doesn't change how much weight people lose in the short term, it can make a difference in the long run.
Methodology
A systematic review and meta-analysis were conducted, including studies of bariatric surgery patients with liver impairment data and weight loss data at follow-up of 6 months or longer.
Potential Biases
Potential publication bias due to incomplete data reporting and variability in study methodologies.
Limitations
Variability in age, BMI, and sex distribution among studies may affect generalizability; many studies lacked complete data on liver status.
Participant Demographics
Patients undergoing bariatric surgery with varying degrees of obesity and liver disease.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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