Nondipping in Parkinson's Disease
Author Information
Author(s): Sita Sommer, Billur Aral-Becher, Wolfgang Jost
Primary Institution: Universitätsmedizin Mainz
Hypothesis
The study aims to identify patients with Parkinson's disease who show loss or decrease of nocturnal blood pressure fall as a marker of autonomic dysfunction.
Conclusion
The study found a high prevalence of nondipping in patients with Parkinson's disease, indicating it may be a useful marker of autonomic dysfunction.
Supporting Evidence
- 88% of the patients were identified as nondippers.
- 95% of patients with orthostatic hypotension were nondippers.
- 79% of patients without orthostatic hypotension were also nondippers.
Takeaway
Most people with Parkinson's disease don't have a normal drop in blood pressure at night, which can be a sign of problems with their nervous system.
Methodology
40 patients with Parkinson's disease underwent 24-hour blood pressure monitoring to assess nocturnal blood pressure patterns.
Limitations
The study did not include healthy controls for comparison.
Participant Demographics
20 males and 20 females, aged 41 to 82 years, mean age 69.9 years.
Digital Object Identifier (DOI)
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