Arresting Early Childhood Caries with Silver Diamine Fluoride Gel Among Preschool Children: Protocol for a Randomised Clinical Trial
2024

Using Silver Diamine Fluoride Gel to Treat Early Childhood Cavities

Sample size: 630 publication Evidence: high

Author Information

Author(s): Cheng Anthony Yihong, Chen Jieyi, Zheng Faith Miaomiao, Duangthip Duangporn, Chu Chun Hung

Primary Institution: Faculty of Dentistry, The University of Hong Kong

Hypothesis

The 38% SDF gel is not worse than the 38% SDF solution by a non-inferiority margin of 10% caries-arrest rate when applied semi-annually to preschool children.

Conclusion

The 38% SDF gel is cost-effective, non-invasive, and can be widely recommended for caries control.

Supporting Evidence

  • Silver diamine fluoride is effective in managing early childhood caries.
  • The study aims to provide clinical evidence for the adoption of SDF gel in managing ECC.
  • Children with untreated dental carious lesions are more likely to experience severe caries in adulthood.
  • Traditional restorative methods for preventing ECC are not widely available or affordable.
  • The 38% SDF gel can be applied quickly and precisely to carious lesions.

Takeaway

This study is testing a new gel to help stop cavities in young children, comparing it to a liquid that is already used.

Methodology

This is a 30-month, randomised, active-controlled, parallel-group non-inferiority pragmatic clinical trial with two arms.

Potential Biases

Potential bias may arise from the blinding process and the subjective nature of parental reporting.

Limitations

The study may face challenges in recruiting enough participants and ensuring compliance over the 30-month period.

Participant Demographics

Children aged 3 to 4 years old attending kindergarten.

Digital Object Identifier (DOI)

10.3390/dj12120419

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication