Geographic distribution of lung and stomach cancers in England and Wales over 50 years: changing and unchanging patterns
1991

Geographic Distribution of Lung and Stomach Cancers in England and Wales

Sample size: 360011 publication Evidence: moderate

Author Information

Author(s): A.J. Swerdlow, I. dos Santos Silva

Primary Institution: London School of Hygiene and Tropical Medicine

Hypothesis

The study aims to analyze the geographic distribution of lung and stomach cancers in England and Wales over a 50-year period.

Conclusion

The geographic distribution of lung and stomach cancers has changed significantly over the past 50 years, with notable increases in risk in northern regions.

Supporting Evidence

  • The study found that stomach cancer risks in North Wales have diminished but remain high.
  • Lung cancer patterns have shifted from London to northern regions for younger populations.
  • Postneonatal mortality rates correlated significantly with stomach cancer risks.

Takeaway

This study looked at where lung and stomach cancers happen in England and Wales and found that the places with the most cases have changed a lot over time.

Methodology

Data from the national cancer registry was analyzed for lung and stomach cancer incidence by county from 1968-81, adjusting for urbanization.

Potential Biases

Potential bias due to variations in cancer registration completeness across different counties.

Limitations

The study's data collection methods varied by region, which could affect the completeness of cancer registration.

Participant Demographics

The study included cancer cases from both males and females across various age groups.

Statistical Information

P-Value

p<0.001

Confidence Interval

1.13-1.18

Statistical Significance

p<0.001

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