Survey of Canadian Animal-Based Researchers' Views on the Three Rs: Replacement, Reduction and Refinement
2011

Survey of Canadian Animal-Based Researchers' Views on the Three Rs: Replacement, Reduction and Refinement

Sample size: 414 publication 10 minutes Evidence: moderate

Author Information

Author(s): Fenwick Nicole, Danielson Peter, Griffin Gilly

Primary Institution: Canadian Council on Animal Care

Hypothesis

What are the views of Canadian animal-based researchers on the Three Rs and what obstacles and opportunities exist for their implementation?

Conclusion

Researchers generally do not view the goal of replacement as achievable and prefer to use enough animals to ensure quality data.

Supporting Evidence

  • Participants expressed concerns that further reduction of animal numbers may compromise research quality.
  • Many researchers feel that they already reduce animal numbers as much as possible.
  • Support for the Three Rs strategy of conducting animal welfare-related pilot studies was strong among participants.

Takeaway

This study asked researchers how they feel about using animals in experiments and found that many think it's hard to replace animals with other methods.

Methodology

A web-based survey was conducted to gather views from Canadian animal-based researchers on the Three Rs.

Potential Biases

Potential bias due to self-selection of participants and the nature of the survey questions.

Limitations

The response rate was low, and many participants expressed confusion over survey questions.

Participant Demographics

{"principal_investigators":{"count":298,"gender_distribution":{"female":30.9,"male":67.5},"age_distribution":{"19-29":1,"30-39":15.4,"40-49":34.9,"50-59":32.2,"60-above":15.8},"education":{"PhD":89.9,"Masters":3.7,"College/university":5.0}},"other_researchers":{"count":116,"gender_distribution":{"female":65.5,"male":33.6},"age_distribution":{"19-29":34.5,"30-39":32.8,"40-49":15.5,"50-59":15.5,"60-above":0.9},"education":{"PhD":39.7,"Masters":30.2,"College/university":30.2}}}

Digital Object Identifier (DOI)

10.1371/journal.pone.0022478

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