Up-Beat UK: A programme of research into the relationship between coronary heart disease and depression in primary care patients
2011

Research on Coronary Heart Disease and Depression

Sample size: 800 publication Evidence: moderate

Author Information

Author(s): Tylee André, Ashworth Mark, Barley Elizabeth, Brown June, Chambers John, Farmer Anne, Fortune Zoe, Haddad Mark, Lawton Rebecca, Mann Anthony, Mehay Anita, McCrone Paul, Murray Joanna, Leese Morven, Pariante Carmine M, Rose Diana, Rowlands Gill, Smith Alison, Walters Paul

Primary Institution: Institute of Psychiatry, King's College London

Hypothesis

The severity of symptoms of coronary heart disease is a greater predictor of developing a depressive episode than a past history of depression.

Conclusion

The study aims to explore the relationship between coronary heart disease and depression, providing insights for better management in primary care.

Supporting Evidence

  • Coronary heart disease and depression are predicted to be the top causes of global health burden by 2020.
  • Depression is more common in patients with coronary heart disease, with a prevalence of 20%.
  • Depression increases the incidence and recurrence of acute coronary syndromes and death in heart disease patients.

Takeaway

This study is trying to understand how heart disease and depression are connected so doctors can help patients better.

Methodology

The research consists of a 4-year cohort study, qualitative studies, and a pilot randomized controlled trial.

Limitations

Recruitment rates into the cohort study may vary widely, potentially affecting representativeness.

Participant Demographics

Patients with coronary heart disease, including those with and without depression, aged over 18.

Digital Object Identifier (DOI)

10.1186/1471-2296-12-38

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