Rising Breast Cancer Rates in Female Cancer Survivors
Author Information
Author(s): Soerjomataram I, Louwman W J, Duijm L E M, Coebergh J W W
Primary Institution: Erasmus MC
Hypothesis
Is there an increasing incidence of breast cancer among female cancer survivors over time?
Conclusion
The study found a significant increase in breast cancer incidence among female cancer survivors, particularly for those who had non-breast cancers.
Supporting Evidence
- The incidence rate of breast cancer among female cancer survivors increased by 30% over 15 years.
- Non-breast cancer survivors had a significantly worse stage distribution compared to breast cancer survivors.
- The rate of second breast cancer stage II tripled during the study period.
Takeaway
More women who survived other cancers are now getting breast cancer, so we need to check them more often to catch it early.
Methodology
The study analyzed data from a population-based cancer registry, comparing breast cancer incidence in two cohorts of female cancer survivors diagnosed in different decades.
Potential Biases
Potential biases may arise from the reliance on registry data and the exclusion of certain cancer types.
Limitations
The study only followed patients for 10 years, which may have missed late effects of treatment.
Participant Demographics
The study included female cancer survivors aged 30 and older, diagnosed with primary cancer between 1975-1979 and 1990-1994.
Statistical Information
P-Value
0.005
Confidence Interval
95% CI: 1.03–1.68
Statistical Significance
p=0.005
Digital Object Identifier (DOI)
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