Grey-Blue Regression in Melanoma In Situ—Evaluation on 111 Cases
2011

Grey-Blue Regression in Melanoma In Situ

Sample size: 111 publication Evidence: moderate

Author Information

Author(s): S. Bassoli, S. Borsari, C. Ferrari, F. Giusti, G. Pellacani, G. Ponti, S. Seidenari

Primary Institution: Department of Dermatology, University of Modena and Reggio Emilia, Modena, Italy

Hypothesis

The study aims to assess the frequency and extent of dermoscopic features of regression in melanoma in situ.

Conclusion

The identification of the reticular pattern of blue regression is a significant discriminator and a reliable predictor of melanoma in situ.

Supporting Evidence

  • Regression structures were present in 80.1% of the lesions.
  • Approximately 80% of the lesions showed regression of dermoscopic structures and light brown areas.
  • Most lesions showed the presence of grey-blue areas (74.7%).
  • Peppering was observable in 30.6% of melanoma in situ cases.
  • Areas of fibrosis were mainly observable as structureless areas with a pinkish hue (50.4%).

Takeaway

Doctors looked at pictures of skin lesions to see how often certain signs of melanoma were present, and they found that most lesions showed signs of regression.

Methodology

The study evaluated dermoscopic images of 111 melanomas in situ for the presence of 11 regression parameters assessed by three dermatologists.

Limitations

The study may have limitations related to the subjective interpretation of dermoscopic images.

Participant Demographics

The lesions were from 110 patients (50 female and 60 male) with a mean age of 56.4 years.

Digital Object Identifier (DOI)

10.1155/2011/180980

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