Vardenafil for Treating Tinnitus: A Pilot Study
Author Information
Author(s): Mazurek Birgit, Haupt Heidemarie, Szczepek Agnieszka J, Sandmann Jörg, Gross Johann, Klapp Burghard F, Kiesewetter Holger, Kalus Ulrich, Stöver Timo, Caffier Philipp P
Primary Institution: Charité – Universitätsmedizin Berlin
Hypothesis
Does vardenafil have a therapeutic effect on chronic tinnitus?
Conclusion
Vardenafil did not show superior efficacy over placebo in treating chronic tinnitus.
Supporting Evidence
- Vardenafil did not improve tinnitus scores compared to placebo.
- Safety profile of vardenafil was consistent with previous studies.
- Participants reported no significant changes in quality of life measures.
Takeaway
The study tested a medicine called vardenafil to see if it could help people with ringing in their ears, but it didn't work better than a sugar pill.
Methodology
A randomized, double-blind, placebo-controlled trial with 42 subjects receiving either vardenafil or placebo for 12 weeks.
Potential Biases
Potential biases in self-reported outcomes and the small sample size.
Limitations
The study was small and only lasted 12 weeks, which may not be sufficient to observe long-term effects.
Participant Demographics
Participants were adults aged 18 to 65 with chronic tinnitus, predominantly Caucasian.
Digital Object Identifier (DOI)
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