Effects of a Carbohydrate-Restricted Diet on Cardiovascular Disease Markers
Author Information
Author(s): Richard J. Wood, Jeff S. Volek, Steven R. Davis, Carly Dell'Ova, Maria Luz Fernandez
Primary Institution: University of Connecticut
Hypothesis
Carbohydrate-restricted diets will improve emerging risk factors for cardiovascular disease.
Conclusion
A carbohydrate-restricted diet leads to weight loss and improvements in several cardiovascular disease risk markers in overweight men.
Supporting Evidence
- A carbohydrate-restricted diet led to a mean weight loss of 7.5 kg.
- Plasma Lp(a) levels decreased significantly in 76% of subjects.
- CRP and TNF-α levels were reduced in 69% and 76% of subjects, respectively.
- Energy intake was spontaneously reduced by 718 kcal/day.
- Participants showed a significant reduction in trans fatty acid intake.
Takeaway
Eating fewer carbs can help people lose weight and make their hearts healthier.
Methodology
29 overweight men followed a carbohydrate-restricted diet for 12 weeks, with some receiving fiber supplements.
Limitations
Results are limited to overweight men who are otherwise healthy.
Participant Demographics
Overweight men aged 20-69 with a BMI of 25-35 kg/m2.
Statistical Information
P-Value
P < 0.001 for energy intake reduction; P < 0.05 for Lp(a), CRP, and TNF-α reductions.
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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