Using MRI to Predict Heart Problems in Patients with Defibrillators
Author Information
Author(s): Gao Peng, Yee Raymond, Hogg Ellie, Stirrat John, Scholl David, Gula Lorne, Krahn Andrew D, Skanes Allan, Leong-Sit Peter, Klein George, White James A
Primary Institution: London Health Sciences Centre – Division of Cardiology, London, ON, Canada
Hypothesis
Can delayed enhancement MRI predict arrhythmic events in primary prevention ICD candidates regardless of the type of cardiomyopathy?
Conclusion
Total scar mass is a significant predictor of arrhythmic events in patients considered for primary prevention ICDs, regardless of whether they have ischemic or non-ischemic cardiomyopathy.
Supporting Evidence
- 76 patients received an ICD during the study.
- 16 patients experienced a primary endpoint, including 15 ICD therapies and 1 aborted SCA.
- Total scar mass was significantly higher in patients with primary and secondary outcomes.
Takeaway
Doctors can use a special MRI to see how much scar tissue is in the heart, which helps them figure out if patients might have serious heart problems later.
Methodology
125 patients underwent DE MRI and were followed for primary and secondary endpoints related to ICD therapy and sudden cardiac arrest.
Participant Demographics
Mean age was 61.4 years, with 61 patients having ischemic cardiomyopathy and 64 having non-ischemic cardiomyopathy.
Statistical Information
P-Value
p<0.001
Confidence Interval
0.73~0.96
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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