Growth pattern of ductal carcinoma in situ (DCIS): a retrospective analysis based on mammographic findings
2001
Growth Patterns of Ductal Carcinoma in Situ
Sample size: 39
publication
Evidence: moderate
Author Information
Author(s): Thomson J Z, Evans A J, Pinder S E, Burrell H C, Wilson A R M, Ellis I O
Primary Institution: City Hospital, Nottingham, UK
Hypothesis
The study aims to obtain information concerning the direction and rates of growth of ductal carcinoma in situ (DCIS).
Conclusion
DCIS grows toward the nipple at a faster rate than in other directions, and growth rates increase with the nuclear grade of DCIS.
Supporting Evidence
- The study examined mammograms of 124 women diagnosed with DCIS.
- 39 women had calcifications visible on both current and prior examinations.
- Growth rates were calculated for calcifications along different axes.
- Growth toward the nipple occurred at a mean rate of 5.5 mm per year.
Takeaway
The study looked at how a type of breast cancer called DCIS grows, finding it grows faster toward the nipple.
Methodology
The previous mammograms of 124 women diagnosed with DCIS were examined to analyze calcification growth.
Participant Demographics
Women diagnosed with DCIS.
Digital Object Identifier (DOI)
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