Impact of ICU-Acquired Infections on Hospital Mortality
Author Information
Author(s): Pekka Ylipalosaari, Tero Ala-Kokko, Jouko Laurila, Pasi Ohtonen, Hannu Syrjälä
Primary Institution: Oulu University Hospital
Hypothesis
Does ICU-acquired infection increase the risk of hospital mortality?
Conclusion
ICU-acquired infection was found to be an independent risk factor for hospital mortality.
Supporting Evidence
- 80 out of 335 patients developed ICU-acquired infections.
- Hospital mortality was higher in patients with ICU-acquired infections regardless of infection status on admission.
- ICU-acquired infection increased hospital stay significantly.
Takeaway
Getting an infection while in the ICU can make you much more likely to die in the hospital.
Methodology
Patients with a stay longer than 48 hours in a mixed ICU were prospectively enrolled and analyzed for risk factors of hospital mortality using logistic regression.
Potential Biases
Potential biases may arise from the observational nature of the study and the lack of randomization.
Limitations
The study was observational and did not include patients with ICU readmissions or incomplete data.
Participant Demographics
Patients admitted to a 10-bed mixed medical-surgical ICU, with a median age of 59 years.
Statistical Information
P-Value
0.008; 0.023; p < 0.001
Confidence Interval
95% CI: 2.0–7.9; 95% CI: 2.9–7.6
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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