Three-dimensional and two-dimensional echocardiography and biochemical analysis in patients with ST-segment elevation myocardial infarction percutaneously treated: relationship between LV function, remodeling and serum cardiac markers
2011

Echocardiography and Cardiac Markers in Heart Attack Patients

Sample size: 23 publication Evidence: moderate

Author Information

Author(s): Vieira MLC, Oliveira WA, Cury AF, Cordovil A, Rodrigues ACT, Naccarato G, Mônaco CG, Costa LPRV, Romano RB, Calatróia JR, Afonso TR, Azevedo REU, Tavares GMP, Guimarães L, Lira Filho EB, Perin MA, Fischer CH, Morhy SS

Primary Institution: Hospital Israelita Albert Einstein, São Paulo - SP, Brazil

Hypothesis

The study aims to assess the relationship between serum markers of cardiac damage and echocardiographic parameters in patients with acute ST-elevation myocardial infarction.

Conclusion

The study found a stronger correlation between serum CK-MB, BNP, and 3D Echo LVEF compared to 2D Echo LVEF.

Supporting Evidence

  • 3D SPI ranged from 0.29 to 0.45 with a mean of 0.35.
  • 3D LVEF ranged from 0.36 to 0.70 with a mean of 0.50.
  • Troponin I levels ranged from 2.3 to 33 ng/ml with a mean of 12.9 ng/ml.
  • CK-MB levels ranged from 5.7 to 258 ng/ml with a mean of 94.4 ng/ml.
  • BNP levels ranged from 25 to 1,058 pg/ml with a mean of 264 pg/ml.

Takeaway

Doctors looked at heart scans and blood tests to see how they relate in patients who had a heart attack. They found that some blood tests were better at showing heart function than others.

Methodology

A prospective study comparing serum cardiac markers and echocardiographic parameters in patients with acute ST-elevation MI.

Participant Demographics

23 patients (17 males, mean age of 57 ± 13 years)

Statistical Information

P-Value

0.4800

Confidence Interval

95% CI

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/cc10173

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