Nutraceutical Properties of Thai Mulberry (Morus alba L.) and Their Effects on Metabolic and Cardiovascular Risk Factors in Individuals with Obesity: A Randomized, Single-Blind Crossover Trial
2024

Effects of Thai Mulberry Drink on Obesity and Heart Health

Sample size: 12 publication 10 minutes Evidence: moderate

Author Information

Author(s): Parklak Wason, Chottidao Monchai, Munkong Narongsuk, Komindr Surat, Monkhai Sudjai, Wanikorn Bandhita, Makaje Niromlee, Kulprachakarn Kanokwan, Chuljerm Hataichanok, Somnuk Surasawadee, Bordiga Matteo, Oliveira Hélder

Primary Institution: Kasetsart University, Kamphaeng Saen Campus

Hypothesis

Does a concentrated mulberry drink improve metabolic and cardiovascular risk factors in obese individuals?

Conclusion

The study found that the mulberry drink significantly reduced blood pressure, triglycerides, and fasting plasma glucose levels in obese individuals.

Supporting Evidence

  • Participants showed significant reductions in systolic and diastolic blood pressure after consuming the mulberry drink.
  • Triglyceride levels were significantly lower during the mulberry drink phase compared to the placebo.
  • Fasting plasma glucose levels increased during the placebo phase but remained stable during the mulberry drink phase.
  • C-reactive protein levels, an inflammation marker, were significantly lower during the mulberry drink consumption.

Takeaway

Drinking a special mulberry juice can help people who are overweight lower their blood pressure and sugar levels.

Methodology

A randomized, single-blind crossover trial where participants consumed a concentrated mulberry drink daily for 6 weeks, alternating with a placebo.

Potential Biases

Potential bias due to the small sample size and dropout rate.

Limitations

The study had a dropout rate of approximately 20%, which may affect the reliability of the results.

Participant Demographics

12 participants (7 men, 5 women), aged 30-55 years, with a BMI of 32.1 ± 5.98 kg/m2.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/nu16244336

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