Emergence of Haemophilus influenzae Strains in the Nasopharynx of Children with Tuberculosis
2011

Haemophilus influenzae in Children with Tuberculosis

Sample size: 85 publication Evidence: moderate

Author Information

Author(s): Martynova Alina V., Balabanova Larisa A., Pruschinskyi Alexei

Primary Institution: State Vladivostok Medical University

Hypothesis

What is the prevalence of Haemophilus influenzae in the nasopharynx of children with tuberculosis?

Conclusion

Children treated for tuberculosis often carry Haemophilus influenzae, which is frequently underestimated.

Supporting Evidence

  • Children with tuberculosis carried H. influenzae more often than those without tuberculosis.
  • 51 strains of H. influenzae were isolated from 43 patients in the tuberculosis group.
  • Children in the tuberculosis group had a higher rate of multiple strains of H. influenzae.

Takeaway

This study found that many kids with tuberculosis also have a germ called Haemophilus influenzae, which can make them sick.

Methodology

The study examined nasopharyngeal swabs from 85 children with tuberculosis and a control group of 70 children without tuberculosis.

Limitations

The study may not account for all factors influencing bacterial carriage in children with tuberculosis.

Participant Demographics

Children aged 1.5-15 years, with a control group of age-matched children without tuberculosis.

Statistical Information

P-Value

0.003

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1155/2011/420284

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