Impact of Malaria Control in Zanzibar
Author Information
Author(s): Aregawi Maru W, Ali Abdullah S, Al-mafazy Abdul-wahiyd, Molteni Fabrizio, Katikiti Samson, Warsame Marian, Njau Ritha JA, Komatsu Ryuichi, Korenromp Eline, Hosseini Mehran, Low-Beer Daniel, Bjorkman Anders, D'Alessandro Umberto, Coosemans Marc, Otten Mac
Primary Institution: World Health Organization, Global Malaria Programme
Hypothesis
The scale-up of malaria control interventions will significantly reduce malaria and anaemia cases and deaths in Zanzibar.
Conclusion
Scaling-up effective malaria interventions reduced malaria-related burden at health facilities by over 75% within 5 years.
Supporting Evidence
- Malaria deaths fell by an estimated 90% in 2008 compared to the pre-intervention period.
- Malaria in-patient cases decreased by 78% and parasitologically-confirmed malaria out-patient cases by 99.5%.
- Anaemia in-patient cases decreased by 87%.
Takeaway
When Zanzibar started using better treatments and prevention for malaria, many fewer people got sick or died from it.
Methodology
The study compared outpatient and inpatient cases and deaths between 2008 and the pre-intervention period 1999-2003 using segmented log-linear regression.
Potential Biases
Health facility-based data may not reflect trends in malaria burden at the population level.
Limitations
The use of a five-year period as reference may not provide a stable pre-intervention baseline.
Participant Demographics
The study included patients from six out of seven in-patient health facilities in Zanzibar.
Statistical Information
P-Value
p<0.025
Confidence Interval
95% CI 55-98%
Statistical Significance
p<0.025
Digital Object Identifier (DOI)
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