Biochemical studies of some diagnostic enzymes in myocardial infarction
2011

Diagnostic Enzymes in Myocardial Infarction

Sample size: 90 publication Evidence: moderate

Author Information

Author(s): Samir M, Nagi H Khaled, Ragab D, Refaie M

Primary Institution: Cairo University

Hypothesis

The study aims to demonstrate the role of arginase and adenosine deaminase (ADA) in patients suffering from myocardial infarction and chronic renal failure with cardiovascular diseases.

Conclusion

ADA is a good diagnostic enzyme for patients suffering from myocardial infarction and chronic renal failure with cardiovascular diseases.

Supporting Evidence

  • The mean serum arginase enzyme activity was significantly higher in myocardial infarction patients compared to the control group.
  • ADA levels were also significantly elevated in myocardial infarction patients compared to controls.

Takeaway

Doctors can use certain enzymes to help diagnose heart attacks and kidney problems in patients.

Methodology

This was a prospective study including 90 subjects divided into three groups: myocardial infarction patients, chronic renal failure patients with cardiovascular diseases, and normal volunteers.

Participant Demographics

30 patients with myocardial infarction, 30 patients with chronic renal failure, and 30 normal volunteers.

Statistical Information

P-Value

p<0.001

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1186/cc9423

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