Imitating manual curation of text-mined facts in biomedicine
2006

AI Curation in Biomedicine

Sample size: 100000 publication Evidence: high

Author Information

Author(s): Rodriguez-Esteban Raul, Iossifov Ivan, Rzhetsky Andrey

Primary Institution: Columbia University

Hypothesis

Using a larger number of human experts to evaluate any given sentence could allow for an artificial-intelligence curator to perform the classification job at least as accurately as an average individual human evaluator.

Conclusion

The study developed an AI program that closely approaches human experts in accurately distinguishing correctly extracted facts from incorrectly extracted ones.

Supporting Evidence

  • The AI program achieved a ROC score close to 0.95, indicating high accuracy.
  • The study used almost 100,000 independent evaluations to train the AI.
  • The AI's performance was statistically indistinguishable from that of human evaluators.

Takeaway

Scientists created a computer program that can check facts in medical texts almost as well as humans can.

Methodology

The study used machine learning techniques to analyze a large training set of manually evaluated facts to develop an AI tool for fact evaluation.

Potential Biases

The training data may not represent all types of biological relationships, potentially affecting the AI's performance.

Limitations

The study's approach is biased toward relationships captured by the GeneWays system, which may not generalize to all biomedical texts.

Participant Demographics

The evaluations were performed by a team of human curators, including biology-savvy doctoral-level curators.

Statistical Information

P-Value

0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pcbi.0020118

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