Predictors of Complications in Ileal Pouch-Anal Anastomosis for Ulcerative Colitis
Author Information
Author(s): Muacevic Alexander, Adler John R, Sarangi Yajnadatta, Kumar Ashok, Malage Somanath, Ghosh Nalinikanta, Rahul Rahul, Singh Ashish, Sharma Supriya, Singh Rajneesh K, Behari Anu
Primary Institution: Sanjay Gandhi Postgraduate Institute of Medical Sciences
Hypothesis
What are the early and late complications of ileal pouch-anal anastomosis in patients with ulcerative colitis and the factors associated with these complications?
Conclusion
The most common early and late complications following IPAA were pelvic sepsis and pouchitis, respectively, with no significant predictive factors for early complications.
Supporting Evidence
- 71.3% of patients experienced early complications within 30 days.
- Pouchitis was the most common late complication, affecting 36.6% of patients.
- Pelvic sepsis was significantly associated with anastomotic stricture.
- Hand-sewn anastomosis was linked to pouch-vaginal fistulae.
- 10.9% of patients experienced pouch failure.
- Patients reported an average stool frequency of 6.18 per day.
- 75.3% of patients were satisfied or very satisfied with the surgery.
- Complications were managed successfully with an acceptable pouch failure rate.
Takeaway
This study looked at patients who had surgery for ulcerative colitis and found that many had complications, especially infections, but doctors can help manage these issues.
Methodology
Data from 101 patients who underwent IPAA for ulcerative colitis were analyzed for early and late complications and their predictive factors.
Potential Biases
Potential misclassification and bias due to retrospective data collection.
Limitations
The study's retrospective design may introduce bias, and the sample size is smaller compared to Western studies.
Participant Demographics
{"median_age":32,"sex_distribution":{"male":69,"female":32},"comorbidities":{"diabetes":5,"hypertension":3,"epilepsy":2,"asthma":2,"hyperthyroidism":1,"coronary_artery_disease":1}}
Statistical Information
P-Value
0.041
Confidence Interval
1.041-7.022
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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