NemaPath: A Tool for Nematode Metabolic Pathways
Author Information
Author(s): Wylie Todd, Martin John, Abubucker Sahar, Yin Yong, Messina David, Wang Zhengyuan, McCarter James P, Mitreva Makedonka
Primary Institution: The Genome Center at Washington University School of Medicine
Conclusion
NemaPath provides a unique resource for visualizing metabolic pathways of multiple nematode species.
Supporting Evidence
- NemaPath hosts metabolic pathway mappings for 30 nematode species.
- The tool allows for systematic study of nematode transcriptomes via enzyme pathway associations.
- NemaPath integrates with other nematode information resources.
Takeaway
NemaPath is like a map that helps scientists understand how different nematodes use their genes to make energy and grow.
Methodology
NemaPath uses a backend tool to align nematode genomic sequences against the KEGG protein database and a web application to display pathway maps.
Limitations
The associations made by NemaPath are putative and based on automated methods, which may not account for all biological nuances.
Digital Object Identifier (DOI)
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