Measuring Microvascular Obstruction in Heart Patients
Author Information
Author(s): Mikami Yoko, Kumar Andreas, Ferreira Vanessa M, Traboulsi Mouhieddin, Anderson Todd J, Friedrich Matthias G
Primary Institution: Stephenson Cardiovascular MR Centre, Libin Cardiovascular Institute of Alberta, Calgary, AB, Canada
Hypothesis
Which standardized definition of hypoenhancement is appropriate to evaluate the presence and extent of microvascular obstruction on first pass perfusion images?
Conclusion
Standard late enhancement images underestimate the size of myocardial areas with microvascular obstruction in patients with acute, reperfused myocardial infarction.
Supporting Evidence
- Microvascular obstruction is linked to poor heart recovery after a heart attack.
- Different imaging techniques can show varying sizes of microvascular obstruction.
- Using a threshold of -2SD provides a reliable measure of microvascular obstruction size.
Takeaway
Doctors can use special heart scans to see how much damage there is in the heart after a heart attack, but some methods might show less damage than there really is.
Methodology
The study analyzed rest first-pass perfusion images, early contrast enhanced images, and late contrast enhanced images in patients with reperfused acute myocardial infarction.
Participant Demographics
Patients with reperfused acute myocardial infarction.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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