Induction of Labour vs. Expectant Monitoring in Pregnant Women with Hypertension
Author Information
Author(s): Koopmans Corine M, Bijlenga Denise, Aarnoudse Jan G, van Beek Erik, Bekedam Dick J, van den Berg Paul P, Burggraaff Jan M, Birnie Erwin, Bloemenkamp Kitty WM, Drogtrop Addi P, Franx Arie, de Groot Christianne JM, Huisjes Anjoke JM, Kwee Anneke, le Cessie Saskia, van Loon Aren J, Mol Ben WJ, van der Post Joris AM, Roumen Frans JME, Scheepers Hubertina CJ, Spaanderman Marc EA, Stigter Rob H, Willekes Christine, van Pampus Maria G
Primary Institution: University Medical Centre Groningen, The Netherlands
Hypothesis
Induction of labour will reduce maternal morbidity and mortality in women with pregnancy induced hypertension or mild preeclampsia at term.
Conclusion
The trial aims to determine if induction of labour is an effective treatment to prevent severe maternal complications in women with pregnancy induced hypertension or mild preeclampsia at term.
Supporting Evidence
- Hypertensive disorders complicate 10 to 15% of all pregnancies at term.
- Induction of labour might prevent maternal and neonatal complications.
- The study aims to show a reduction in severe maternal complications from 12% to 6%.
Takeaway
This study is trying to find out if starting labor early helps pregnant women with high blood pressure have healthier outcomes for themselves and their babies.
Methodology
A multi-centre randomised controlled trial comparing induction of labour with expectant management in women with pregnancy induced hypertension or mild preeclampsia at term.
Potential Biases
Potential bias due to the inability to blind participants and healthcare providers to the treatment allocation.
Limitations
The study may not account for all potential confounding factors and the open-label design may introduce bias.
Participant Demographics
Women aged 18 and older with pregnancy induced hypertension or mild preeclampsia at gestational ages between 36+0 and 41+0 weeks.
Digital Object Identifier (DOI)
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