Widespread Prophages Related to Marine Phage PM2 in Aquatic Bacteria
Author Information
Author(s): Krupovič Mart, Bamford Dennis H
Primary Institution: University of Helsinki
Hypothesis
Can viruses be grouped into lineages based on their genetic determinants?
Conclusion
The study shows that the abundance of PM2-like viruses in aquatic environments may be underestimated and that genes for viral genome replication and host cell lysis belong to a 'nonself' category.
Supporting Evidence
- Thirteen putative prophages related to bacteriophage PM2 were identified in eleven aquatic proteobacteria.
- The major coat protein and packaging ATPase were found in all detected corticoviral elements.
- Genes for viral genome replication and host cell lysis were categorized as 'nonself' and can be acquired via horizontal gene transfer.
Takeaway
Scientists found many similar viruses in ocean bacteria, suggesting there are more of these viruses than we thought.
Methodology
Homology-based searches against the nonredundant protein database at NCBI were used to identify putative corticoviral prophages.
Limitations
The study may not account for all types of viruses present in aquatic environments.
Participant Demographics
Aquatic bacteria from the phylum Proteobacteria.
Digital Object Identifier (DOI)
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