Targeting the Tumor Microenvironment: Focus on Angiogenesis
2012
Targeting the Tumor Microenvironment: Focus on Angiogenesis
publication
Evidence: high
Author Information
Author(s): Fan Fengjuan, Schimming Alexander, Jaeger Dirk, Podar Klaus
Primary Institution: National Center for Tumor Diseases (NCT), University of Heidelberg and German Cancer Research Center (DKFZ)
Hypothesis
The study aims to illustrate the interrelationship between tumor cells and the tumor microenvironment, particularly focusing on angiogenesis in tumor progression.
Conclusion
The study highlights the significant role of angiogenesis in cancer treatment and the development of antiangiogenic therapies.
Supporting Evidence
- Angiogenesis is crucial for tumor growth and progression.
- Antiangiogenic agents have changed treatment strategies for various cancers.
- VEGF is a key factor in promoting angiogenesis in tumors.
Takeaway
This study explains how tumors grow by forming new blood vessels and how targeting this process can help treat cancer.
Digital Object Identifier (DOI)
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