Surveillance of Human Adenovirus Types and the Impact of the COVID-19 Pandemic on Reporting — United States, 2017–2023
2024

Impact of COVID-19 on Human Adenovirus Reporting in the US

Sample size: 2241 publication Evidence: moderate

Author Information

Author(s): Abdirizak Fatima MPH, Winn Amber K. MPH, Parikh Rishika MPH, Scobie Heather M. PhD, Lu Xiaoyan MS, Vega Everardo PhD, Almendares Olivia MSPH, Kirking Hannah L. MD, Rose Erica Billig PhD, Silk Benjamin J. PhD

Primary Institution: Centers for Disease Control and Prevention

Conclusion

Reporting of human adenovirus types decreased during and after the COVID-19 pandemic, despite ongoing circulation of the virus.

Supporting Evidence

  • During 2017–2023, six HAdV types accounted for 88.3% of typed specimens.
  • Reporting to NATRS decreased during and after the COVID-19 pandemic.
  • An increase in type 41 reporting was associated with a hepatitis cluster during 2021–2022.
  • Respiratory specimens accounted for 82.3% of all specimens reported.
  • 17% of specimens were identified as outbreak-related.

Takeaway

This study looked at how many cases of a virus called adenovirus were reported in the US from 2017 to 2023, especially during the COVID-19 pandemic, and found that fewer cases were reported even though the virus was still around.

Methodology

The study analyzed data from the National Adenovirus Type Reporting System (NATRS) which included voluntary reports from laboratories on adenovirus typing results.

Potential Biases

HAdV typing is differentially performed on specimens from severe infections and outbreaks, which may skew the data.

Limitations

The data may not be geographically representative due to limited laboratory participation and missing data on typing or collection dates.

Participant Demographics

Specimens were most frequently collected from infants and young children aged 0–4 years, followed by young adults aged 18–29 years.

Digital Object Identifier (DOI)

10.15585/mmwr.mm7350a1

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