Maternal and Fetal Outcomes in Pregnant Women with Hodgkin's Disease
Author Information
Author(s): M. Lishner, D. Zemlickis, P. Degendorfer, T. Panzarella, S.B. Sutcliffe, G. Koren
Primary Institution: The Hospital for Sick Children and Princess Margaret Hospital, Toronto
Hypothesis
Does pregnancy affect the course and survival of women with Hodgkin's disease?
Conclusion
Pregnant women with Hodgkin's disease have similar survival rates and disease stages compared to non-pregnant women with the same condition.
Supporting Evidence
- Twenty-year survival of pregnant women with Hodgkin's Disease was not different from that of their matched controls.
- Pregnant women with Hodgkin's Disease had a similar distribution of disease stages compared to non-pregnant controls.
- The study is the first to use a case-control method to study the outcome of pregnant women with Hodgkin's disease.
Takeaway
This study looked at women with Hodgkin's disease who were pregnant and found that being pregnant didn't make their cancer worse or affect their chances of survival.
Methodology
Historical cohort study comparing pregnant women with Hodgkin's disease to matched non-pregnant controls.
Potential Biases
Potential bias due to the selectivity of matching criteria and the reliance on historical data.
Limitations
The study is limited by the small sample size and the retrospective nature of the data.
Participant Demographics
Mean age of participants was 26.1 years, with a range from 18 to 38 years.
Statistical Information
P-Value
0.6
Statistical Significance
p=0.6
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